As per Intent Market Research, the Gene Synthesis Market was valued at USD 1.8 billion in 2023 and will surpass USD 3.1 billion by 2030; growing at a CAGR of 7.6% during 2024 - 2030.
The gene synthesis market has witnessed significant growth in recent years due to the increasing demand for synthetic biology and genetic research applications. Gene synthesis refers to the process of creating genes artificially, allowing researchers to design and produce genes in a laboratory setting without relying on natural DNA extraction. This market is driven by advancements in biotechnology, the need for personalized medicine, and the rising demand for genetically engineered organisms in various sectors, including healthcare, agriculture, and industrial biotechnology. With a broad range of applications spanning research, therapeutics, and agriculture, the gene synthesis market is expected to continue expanding at a rapid pace.
The rapid growth of genetic research and the increasing number of biotechnology applications across different industries have contributed to the gene synthesis market's growth. Gene synthesis is widely used in gene editing, recombinant protein production, vaccine development, and the synthesis of novel DNA sequences for various therapeutic and research purposes. Additionally, the advancement of synthesis technologies and a growing focus on personalized medicine, particularly in the fields of oncology and genetic disorders, are helping shape the future of gene synthesis. The market's expansion is also facilitated by improved automation, cost reduction, and innovations in the synthesis process, enabling faster, more efficient, and affordable gene synthesis.
Custom Gene Synthesis Drives Market Growth
Custom gene synthesis is the fastest-growing segment in the gene synthesis market due to its increasing adoption in a wide range of applications, particularly in research, diagnostics, and drug development. Custom gene synthesis allows researchers to design and create synthetic genes tailored to their specific needs, providing them with flexibility and precision in genetic research and experimentation. This technology has become essential in various fields, such as synthetic biology, functional genomics, and gene therapy. Custom gene synthesis enables the creation of genes that do not exist naturally, making it a critical tool for advancing medical research, particularly in gene therapy and the development of new treatments.
The growing demand for personalized medicine, where treatments are customized based on an individual’s genetic profile, has further boosted the adoption of custom gene synthesis. Additionally, advancements in technology, such as high-throughput gene synthesis platforms, have reduced the cost and time associated with custom gene creation, making it more accessible to researchers and biotechnology companies. As the need for precise, tailored genetic sequences continues to rise, custom gene synthesis is expected to remain a key driver of growth in the gene synthesis market.
.JPG)
PCR-Based Gene Synthesis Dominates Technology Segment
Among the various technologies in the gene synthesis market, PCR-based gene synthesis holds the largest share, largely due to its widespread use in creating gene sequences quickly and accurately. PCR (polymerase chain reaction) is a technique that amplifies DNA sequences, allowing for the efficient production of genes. PCR-based gene synthesis offers several advantages, including high accuracy, scalability, and versatility in designing and amplifying genes for a wide range of applications, from research to industrial use. This technology is particularly useful for the synthesis of smaller gene fragments and for applications in gene cloning, expression studies, and sequencing.
PCR-based gene synthesis has become a standard method in molecular biology research due to its well-established protocols and cost-effective nature. Researchers and biotechnology companies favor this technology because it can be easily integrated into existing laboratory workflows, offering quick results with minimal resources. As the demand for genetic research continues to grow, PCR-based gene synthesis will remain a crucial technology in the market, supporting the development of new therapeutics, genetic modifications, and synthetic biology innovations.
Therapeutic Applications Are the Leading Application Area
Therapeutic applications are the largest segment in the gene synthesis market, driven by the increasing use of gene therapies and personalized medicine. Gene synthesis plays a pivotal role in the development of gene therapies, which aim to treat or prevent diseases by introducing or altering genetic material within a patient's cells. The growing prevalence of genetic disorders, cancer, and rare diseases has created a strong demand for gene-based therapies, leading to the widespread adoption of gene synthesis in the therapeutic space. Gene synthesis allows for the creation of genes that are used in gene editing techniques, vaccine development, and targeted therapies.
The rise in biopharmaceutical research and the increasing number of clinical trials focused on gene therapies have further fueled the growth of this segment. With advancements in gene editing technologies like CRISPR-Cas9, gene synthesis has become an essential component in the development of new treatments. As the healthcare industry continues to focus on personalized and precision medicine, the demand for gene synthesis in therapeutic applications is expected to grow, contributing significantly to the overall market growth.
North America Remains the Dominant Region
North America is the largest region in the gene synthesis market, driven by the presence of leading biotechnology companies, advanced healthcare infrastructure, and significant research and development activities. The United States, in particular, is a major hub for gene synthesis, with numerous biotech firms and research institutions focusing on genetic research, drug development, and the commercialization of gene therapies. The region’s dominance is also attributed to the high level of healthcare spending, robust regulatory frameworks, and the growing adoption of personalized medicine and gene therapies.
The strong research and development capabilities in North America, coupled with government support for biotechnology innovation, further bolster the region’s position in the gene synthesis market. As gene therapies and personalized medicine continue to advance, North America’s leadership in the biotechnology and pharmaceutical sectors ensures its continued dominance in the global gene synthesis market. The region is expected to maintain its lead due to its strong infrastructure, investment in R&D, and ongoing advancements in genetic research and technology.
.JPG)
Competitive Landscape and Leading Companies
The gene synthesis market is highly competitive, with several key players driving innovation and growth in this space. Leading companies in the market include Thermo Fisher Scientific, GenScript, Integrated DNA Technologies, Twist Bioscience, and Agilent Technologies. These companies are focused on expanding their product portfolios, improving synthesis technologies, and offering customized gene synthesis solutions to meet the evolving needs of researchers, clinicians, and biotechnology firms.
The competitive landscape is marked by continuous advancements in gene synthesis technology, with companies investing heavily in research and development to improve accuracy, speed, and cost-effectiveness. Strategic collaborations, partnerships, and acquisitions are common as companies seek to expand their capabilities and market reach. As the gene synthesis market continues to grow, competition will intensify, with companies striving to provide more efficient, scalable, and innovative solutions for a wide range of applications, including research, therapeutic development, and industrial uses.
List of Leading Companies:
- Thermo Fisher Scientific Inc.
- Genscript Biotech Corporation
- Eurofins Genomics
- Genewiz
- Integrated DNA Technologies (IDT)
- Biomatik
- Twist Bioscience
- Synthace
- DNA Script
- Jena Bioscience GmbH
- Biosyn
- VectorBuilder
- Evonik Industries AG
- Merck KGaA
- LGC Biosearch Technologies
Recent Developments:
- In November 2024, Genscript Biotech Corporation expanded its custom gene synthesis services to offer faster turnaround times for large-scale DNA synthesis.
- In October 2024, Twist Bioscience launched a new suite of gene synthesis kits aimed at enhancing CRISPR gene editing applications for researchers.
- In September 2024, Integrated DNA Technologies introduced a cutting-edge service for synthesizing long DNA sequences for synthetic biology projects.
- In August 2024, Eurofins Genomics announced the acquisition of a new lab facility to scale up its gene synthesis capacity for industrial applications.
- In July 2024, Thermo Fisher Scientific entered into a partnership with a major biotech company to improve the efficiency of gene synthesis for drug development.
Report Scope:
|
Report Features |
Description |
|
Market Size (2023) |
USD 1.8 billion |
|
Forecasted Value (2030) |
USD 3.1 billion |
|
CAGR (2024 – 2030) |
7.6% |
|
Base Year for Estimation |
2023 |
|
Historic Year |
2022 |
|
Forecast Period |
2024 – 2030 |
|
Report Coverage |
Market Forecast, Market Dynamics, Competitive Landscape, Recent Developments |
|
Segments Covered |
Gene Synthesis Market By Product Type (Gene Synthesis Kits, Custom Gene Synthesis, Oligonucleotides, Plasmid Synthesis), By Technology (PCR-Based Gene Synthesis, Recombinant DNA Technology, Enzyme-Based Synthesis, Chemical Synthesis), By Application Area (Research, Therapeutic Applications, Agricultural Biotechnology, Industrial Applications) |
|
Regional Analysis |
North America (US, Canada, Mexico), Europe (Germany, France, UK, Italy, Spain, and Rest of Europe), Asia-Pacific (China, Japan, South Korea, Australia, India, and Rest of Asia-Pacific), Latin America (Brazil, Argentina, and Rest of Latin America), Middle East & Africa (Saudi Arabia, UAE, Rest of Middle East & Africa) |
|
Major Companies |
Thermo Fisher Scientific Inc., Genscript Biotech Corporation, Eurofins Genomics, Genewiz, Integrated DNA Technologies (IDT), Biomatik, Twist Bioscience, Synthace, DNA Script, Jena Bioscience GmbH, Biosyn, VectorBuilder, Evonik Industries AG, Merck KGaA, LGC Biosearch Technologies |
|
Customization Scope |
Customization for segments, region/country-level will be provided. Moreover, additional customization can be done based on the requirements |
|
A comprehensive market research approach was employed to gather and analyze data on the Gene Synthesis Market . In the process, the analysis was also done to analyze the parent market and relevant adjacencies to measure the impact of them on the Gene Synthesis Market . The research methodology encompassed both secondary and primary research techniques, ensuring the accuracy and credibility of the findings.
.jpg)
Secondary Research
Secondary research involved a thorough review of pertinent industry reports, journals, articles, and publications. Additionally, annual reports, press releases, and investor presentations of industry players were scrutinized to gain insights into their market positioning and strategies.
Primary Research
Primary research involved conducting in-depth interviews with industry experts, stakeholders, and market participants across the E-Waste Management ecosystem. The primary research objectives included:
- Validating findings and assumptions derived from secondary research
- Gathering qualitative and quantitative data on market trends, drivers, and challenges
- Understanding the demand-side dynamics, encompassing end-users, component manufacturers, facility providers, and service providers
- Assessing the supply-side landscape, including technological advancements and recent developments
Market Size Assessment
A combination of top-down and bottom-up approaches was utilized to analyze the overall size of the Gene Synthesis Market . These methods were also employed to assess the size of various subsegments within the market. The market size assessment methodology encompassed the following steps:
- Identification of key industry players and relevant revenues through extensive secondary research
- Determination of the industry's supply chain and market size, in terms of value, through primary and secondary research processes
- Calculation of percentage shares, splits, and breakdowns using secondary sources and verification through primary sources
.jpg)
Data Triangulation
To ensure the accuracy and reliability of the market size, data triangulation was implemented. This involved cross-referencing data from various sources, including demand and supply side factors, market trends, and expert opinions. Additionally, top-down and bottom-up approaches were employed to validate the market size assessment.
NA